| Competition: | Women's First Division |
| Season: | 2010–11 |
| Winners: | Standard Fémina de Liège |
| Relegated: | DV Famkes Merkem Miecroob Veltem |
| Continentalcup1: | UEFA Women's Champions League |
| Continentalcup1 Qualifiers: | Standard Fémina de Liège |
| Biggest Home Win: | Liège 12-0 Merkem |
| Biggest Away Win: | Merkem 1-14 Liège |
| Highest Scoring: | Merkem 1-14 Liège |
| Matches: | 182 |
| Total Goals: | 714 |
| Prevseason: | 2009–10 |
| Nextseason: | 2011–12 |
In the Season 2010-11 of the First Division 14 clubs played in the competition. Two teams promoted from the Second Division, these were GBA-Kontich FC and Miecroob Veltem.
K. Sint-Truidense VV were the defending champions. Standard Fémina de Liège won the championship and qualified for the UEFA Women's Champions League.
DV Famkes Merkem and Miecroob Veltem relegated to the Second Division and shall not return in the First Division the next season.
| Team | Home city | Home ground | |
|---|---|---|---|
| Stade Standard de Liège | |||
| Koning Boudewijnstadion | |||
| Gemeentelijk Sportstadion Zulte | |||
| Oud-Heverlee Leuven | Gemeentelijk Stadion | ||
| DVC Eva's Tienen | Sint-Barbaracomplex | ||
| GBA-Kontich FC | |||
| Club Brugge Dames | |||
| FC Fémina White Star Woluwe | Stade Fallon | ||
| Stayen | |||
| DVC Zuid-West-Vlaanderen | Forestiersstadion | ||
| Miecroob Veltem | |||
| DV Famkes Merkem | De Kouter |