| Date: | February 15–22 |
| Edition: | 34th (Men) / 24th (Women) |
| Category: | ATP World Tour 500 (men) (woman) |
| Surface: | Hard |
| Location: | Memphis, Tennessee, US |
| Venue: | Racquet Club of Memphis |
| Champms: |  Andy Roddick |
| Champws: |  Victoria Azarenka |
| Champmd: | Mardy Fish / Mark Knowles |
| Champwd: | Victoria Azarenka / Caroline Wozniacki |
The 2009 Regions Morgan Keegan Championships and the Cellular South Cup was an ATP World Tour and WTA Tour tennis tournament held at the hardcourts of the Racquet Club of Memphis in Memphis, Tennessee in the United States. It was the 34th edition of the Regions Morgan Keegan Championships and the 24th edition of the Cellular South Cup. The Regions Morgan Keegan Championships was part of the ATP World Tour 500 series on the 2009 ATP World Tour, and the Cellular South Cup was an International-level tournament on the 2009 WTA Tour. Both of the events took place from February 15 to February 22, 2009.
The men's draw was led by Australian Open & San Jose semifinalist plus 2002 champion Andy Roddick, Auckland champion Juan Martín del Potro, San Jose semifinalist plus 2002 runner-up James Blake, Auckland semifinalist and 2006 and 2008 runner-up Robin Söderling, Brisbane titlist Radek Štěpánek, Igor Andreev, Mardy Fish and Auckland runner-up Sam Querrey.
The women's draw was headed by WTA #12 Caroline Wozniacki, Brisbane winner Victoria Azarenka, Lucie Šafářová, Auckland semifinalist Anne Keothavong, Marina Erakovic, Sabine Lisicki, Alla Kudryavtseva and Pauline Parmentier.
| Athlete | Nationality | Ranking* | Seeding | |
|---|---|---|---|---|
| Caroline Wozniacki | Denmark | 12 | 1 | |
| Victoria Azarenka | Belarus | 14 | 2 | |
| Lucie Šafářová |  Czech Republic | 50 | 3 | |
| Anne Keothavong |  Great Britain | 52 | 4 | |
| Marina Erakovic |  New Zealand | 57 | 5 | |
| Sabine Lisicki | Germany | 59 | 6 | |
| Alla Kudryavtseva |  Russia | 62 | 7 | |
| Pauline Parmentier |  France | 86 | 8 |
The following players received wildcards into the main draw:
The following players received entry from the qualifying draw:
| Athlete | Nationality | Ranking* | Seeding | |
|---|---|---|---|---|
| Andy Roddick | United States | 6 | 1 | |
| Juan Martín del Potro |  Argentina | 7 | 2 | |
| James Blake | United States | 13 | 3 | |
| Robin Söderling |  Sweden | 16 | 4 | |
| Radek Štěpánek | Czech Republic | 19 | 5 | |
| Igor Andreev | Russia | 22 | 6 | |
| Mardy Fish | United States | 21 | 7 | |
| Sam Querrey | United States | 37 | 8 |
The following players received wildcards into the main draw:
The following players received entry from the qualifying draw:
See main article: 2009 Regions Morgan Keegan Championships – Singles. Andy Roddick defeated Radek Štěpánek, 7–5, 7–5
See main article: 2009 Cellular South Cup – Singles. Victoria Azarenka defeated Caroline Wozniacki, 6–1, 6–3
See main article: 2009 Regions Morgan Keegan Championships – Doubles. Mardy Fish / Mark Knowles defeated Travis Parrott / 
Filip Polášek, 7–6(9–7), 6–1
See main article: 2009 Cellular South Cup – Doubles. Victoria Azarenka / Caroline Wozniacki defeated 
Yuliana Fedak / Michaëlla Krajicek, 6–1, 7–6(7–2)
