The 2009 Internazionali Femminili di Palermo was a women's tennis tournament played on outdoor clay courts. It is the 22nd edition of the Internazionali Femminili di Palermo, and is part of the WTA International tournaments of the 2009 WTA Tour. It took place in Palermo, Italy, from 13 July until 19 July 2009. First-seeded Flavia Pennetta won the singles title.
| Player | Nationality | Ranking* | Seeding |
|---|---|---|---|
| Flavia Pennetta |  Italy | 15 | 1 |
| Patty Schnyder | Switzerland | 21 | 2 |
| Alizé Cornet | 23 | 3 | |
| Anastasia Pavlyuchenkova |  Russia | 33 | 4 |
| Italy | 38 | 5 | |
| Russia | 41 | 6 | |
 France | 42 | 7 | |
| Gisela Dulko |  Argentina | 45 | 8 |
The following players received wildcards into the singles main draw
The following players received entry from the qualifying draw:
See main article: 2009 Internazionali Femminili di Palermo – Singles. Flavia Pennetta defeated Sara Errani 6–1, 6–2
See main article: 2009 Internazionali Femminili di Palermo – Doubles. 
Nuria Llagostera Vives / María José Martínez Sánchez defeated 
Mariya Koryttseva / 
Darya Kustova, 6–1, 6–2