| Competition: | Liga Nacional de Fútbol de Guatemala |
| Season: | 2009–10 |
| Dates: | August 1, 2009 - May 15, 2010 |
| Winners: | Apertura: Municipal (27th title) Clausura: Municipal (28th title) |
| Relegated: | Jalapa Zacapa |
| Continentalcup1: | CONCACAF Champions League |
| Continentalcup1 Qualifiers: | Municipal Xelajú |
| Prevseason: | 2008–09 |
| Nextseason: | 2010–11 |
The 2009–10 Liga Nacional de Fútbol de Guatemala season is the 11th season in which the Apertura and Clausura season is used.
The format for both championships are identical. Each championship will have two stages: a first stage and a playoff stage. The first stage of each championship is a double round-robin format. The teams that finishes 1 and 2 in the standings will advance to the payoffs semifinals, while the teams that finish 3–6 will enter in the quarterfinals. The winner of each quarterfinals will advance to the semifinals. The winners of the semifinals will advance to the finals, which will determine the tournament champion.
| Team | Home city | Stadium | Capacity |
|---|---|---|---|
| Comunicaciones | Guatemala | Cementos Progreso | 16,000 |
| Heredia | San José | Julian Tesucun | 8,000 |
| Jalapa | Jalapa | Las Flores | 5,000 |
| Juventud Retalteca | Retalhuleu | Óscar Monterroso | 8,000 |
| Marquense | San Marcos | Marquesa de la Ensenada | 10,000 |
| Municipal | Guatemala | Mateo Flores | 30,000 |
| Peñarol La Mesilla | Huehuetenango | Los Cuchumatanes | 5,340 |
| Suchitepéquez | Mazatenango | Carlos Salazar Hijo | 12,000 |
| Universidad San Carlos | Guatemala | Revolución USAC | 5,000 |
| Xelajú | Quetzaltenango | Mario Camposeco | 11,000 |
| Xinabajul | Huehuetenango | Los Cuchumatanes | 5,340 |
| Zacapa | Zacapa | David Ordoñez Bardales | 10,000 |
The Torneo Apertura is the first championship of the season. It began on August 1, 2009, and ended on December 20, 2009.
| width=23 | Pos | Player | Team | Goals |
|---|---|---|---|---|
| 1 |  Henry Javier Hernández | Juventud Retalteca | 19 | |
| 2 | Tránsito Montepeque | Comunicaciones | 14 | |
| 3 | Nelson Martín Crossa | Municipal | 12 | |
| 4 | Mario Castellanos | Heredia | 11 | |
| align=center rowspan=2 | 5 | Freddy García | Heredia | 9 |
| Jonny Jeffersone Brown Fajardo | Marquense | 9 | ||
| align=center rowspan=2 | 7 | Mário Rodriguez | Municipal | 8 |
 Carlos Kamiani Félix | Universidad de San Carlos | 8 | ||
| 9 | Jhonny Cubero | Xelajú | 7 | |
| 10 | Oscar Isaula | Zacapa | 6 |
The Torneo Clausura is the second championship of the season. It began on January 15, 2010, and ended on May 15, 2010.