| Score: | 7–5, 6–4 |
| Draw: | 128 (12 / 8) |
| Seeds: | 32 |
| Before Name: | Wimbledon Championships – Women's singles |
| After Name: | Wimbledon Championships – Women's singles |
See main article: 2008 Wimbledon Championships. Defending champion Venus Williams defeated her sister Serena Williams in the final, 7–5, 6–4 to win the ladies' singles tennis title at the 2008 Wimbledon Championships.[1] It was her fifth Wimbledon title and seventh major singles title overall.[2] She won the title without losing a set, the second time she did so at a major.
Ana Ivanovic, Jelena Janković, Maria Sharapova and Svetlana Kuznetsova were in contention for the WTA No. 1 ranking. Ivanovic retained the top ranking despite losing in the third round to Zheng Jie. Janković, Sharapova and Kuznetsova also lost in the first four rounds, marking the first time in history that none of the top four seeds advanced to the quarterfinals.[3]
Zheng went on to reach the semifinals, becoming the first Chinese player to do so at a singles major, and becoming the first wild card to reach the semifinals.[4] Zheng's win over Ivanovic also made her, as the world No. 133, the lowest-ranked player to defeat a reigning world No. 1; this record would be broken only two months later by Julie Coin at the 2008 US Open, who also defeated Ivanovic. Tamarine Tanasugarn became the first Thai player to reach the quarterfinals of a major.[5]
See also: 1 and 1. 
Ana Ivanovic (third round)
See also: 2 and 8. Jelena Janković (fourth round)
See also: 3 and 6. 
Maria Sharapova (second round)
See also: 4 and 3. Svetlana Kuznetsova (fourth round)
See also: 5 and 5. Elena Dementieva (semifinals)
See also: 6 and 4. 
Serena Williams (final)
See also: 7 and 7. Venus Williams (champion)
See also: 8 and 2. Anna Chakvetadze (fourth round)
See also: 9 and 5. Dinara Safina (third round)
See also: 10 and 7. 
Daniela Hantuchová (second round)
See also: 11 and 4. 
Marion Bartoli (third round)
See also: 12 and 2. Patty Schnyder (first round)
See also: 13 and 8. Vera Zvonareva (second round)
See also: 14 and 3. 
Agnieszka Radwańska (quarterfinals)
See also: 15 and 1. 
Ágnes Szávay (fourth round)
See also: 16 and 6. 
Victoria Azarenka (third round)
See also: 17 and 3. Alizé Cornet (first round)
See also: 18 and 2. 
Nicole Vaidišová (quarterfinals)
See also: 19 and 4. Maria Kirilenko (first round)
See also: 20 and 1. 
Francesca Schiavone (second round)
See also: 21 and 6. Nadia Petrova (quarterfinals)
See also: 22 and 7. Flavia Pennetta (second round)
See also: 23 and 8. Katarina Srebotnik (first round)
See also: 24 and 5. 
Shahar Pe'er (fourth round)
See also: 25 and 5. Lindsay Davenport (second round, withdrew due to a knee injury)
See also: 26 and 6. 
Sybille Bammer (second round)
See also: 27 and 2. Virginie Razzano (first round)
See also: 28 and 3. 
Alona Bondarenko (second round, retired due to a right leg injury)
See also: 29 and 4. Amélie Mauresmo (third round)
See also: 30 and 1. Dominika Cibulková (first round)
See also: 31 and 8. Caroline Wozniacki (third round)
See also: 32 and 7. 
Sania Mirza (second round)
See main article: 2008 Wimbledon Championships – Women's singles qualifying.
| Category | V. Williams | S. Williams | |
|---|---|---|---|
| 1st serve % | 57/91 (63%) | 44/66 (67%) | |
| 1st serve points won | 35 of 57 = 61% | 33 of 44 = 75% | |
| 2nd serve points won | 19 of 34 = 56% | 5 of 22 = 23% | |
| Total service points won | 54 of 91 = 59.34% | 38 of 66 = 57.58% | |
| Aces | 4 | 9 | |
| Double faults | 3 | 1 | |
| Winners | 20 | 23 | |
| Unforced errors | 18 | 25 | |
| Net points won | 17 of 19 = 89% | 12 of 15 = 80% | |
| Break points converted | 4 of 7 = 57% | 2 of 13 = 15% | |
| Return points won | 28 of 66 = 42% | 37 of 91 = 41% | |
| Total points won | bgcolor=98FB989 | 82 | 75 |
| Source | |||