See main article: article and 2008 US Open (tennis).
Nathalie Dechy and Dinara Safina were the defending champions, but Safina chose not to participate, and only Dechy competed that year.
Dechy partnered with Casey Dellacqua, but lost in the first round to Klaudia Jans and Alicja Rosolska.
Cara Black and Liezel Huber won in the final 6–3, 7–6(8–6), against Lisa Raymond and Samantha Stosur.