| Champ: |  CoCo Vandeweghe |
| Runner: |  Gabriela Paz |
| Score: | 7–6(7–3), 6–1 |
See main article: 2008 US Open (tennis).
Kristína Kučová was the defending champion, but did not compete in the juniors that year.
CoCo Vandeweghe won the tournament, defeating Gabriela Paz in the final, 7–6(7–3), 6–1.