| Year: | 2008 |
| Team: | Texas Southern Tigers |
| Sport: | football |
| Conference: | Southwestern Athletic Conference |
| Short Conf: | SWAC |
| Division: | West Division |
| Record: | 4–8 |
| Conf Record: | 1–6 |
| Head Coach: | Johnnie Cole |
| Hc Year: | 1st |
| Def Coach: | L. C. Cole |
| Dc Year: | 1st |
| Stadium: | Alexander Durley Sports Complex Reliant Stadium Delmar Stadium |
The 2008 Texas Southern Tigers football team represented Texas Southern University as a member of the Southwestern Athletic Conference (SWAC) during the 2008 NCAA Division I FCS football season. Led by the first-year head coach Johnnie Cole, the Tigers compiled an overall record of 4–8, with a mark of 1–6 in conference play, and finished fifth in the West Division of the SWAC.