| Champ: |  Maria Sharapova |
| Runner: | Vera Zvonareva |
| Score: | 6–1, 2–6, 6–0 |
| Draw: | 56 |
| Seeds: | 16 |
| Type: | singles doubles |
| After Year: | 2011 |
See main article: 2008 Qatar Ladies Open.
Maria Sharapova defeated Vera Zvonareva in the final, 6–1, 2–6, 6–0 to win the singles tennis title at the 2008 WTA Qatar Open.[1]
Justine Henin was the reigning champion, but she chose not to participate that year.
The top eight seeds receive a bye into the second round.