| Election Name: | 2008 Mississippi Republican presidential primary |
| Country: | Mississippi |
| Flag Image: | Flag of Mississippi (2001–2020).svg |
| Type: | presidential |
| Ongoing: | no |
| Previous Election: | Mississippi Republican primary, 2004 |
| Previous Year: | 2004 |
| Next Election: | Mississippi Republican primary, 2012 |
| Next Year: | 2012 |
| Candidate1: | John McCain |
| Party1: | Republican Party (United States) |
| Home State1: | Arizona |
| Delegate Count1: | 36 |
| Popular Vote1: | 113,074 |
| Percentage1: | 78.91% |
| Outgoing Members: | VT |
| Elected Members: | PA |
| Candidate2: | Mike Huckabee |
| Party2: | Republican Party (United States) |
| Home State2: | Arkansas |
| Delegate Count2: | 0 |
| Popular Vote2: | 17,943 |
| Percentage2: | 12.52% |
The 2008 Mississippi Republican presidential primary took place on March 11, 2008. The only candidates that were still in the race were Senator John McCain, Congressman Ron Paul, and Alan Keyes. John McCain easily won this primary.
| Candidate | Votes | Percentage | Delegates | |
|---|---|---|---|---|
| 113,074 | 78.91% | 36 | ||
| Mike Huckabee | 17,943 | 12.52% | 0 | |
| 5,510 | 3.85% | 0 | ||
| Mitt Romney | 2,177 | 1.52% | 0 | |
| Fred Thompson | 2,160 | 1.51% | 0 | |
| Rudy Giuliani | 945 | 0.66% | 0 | |
| 842 | 0.59% | 0 | ||
| Duncan Hunter | 414 | 0.29% | 0 | |
| Tom Tancredo | 221 | 0.15% | 0 | |
| Total | 143,286 | 100% | 36 |
* Candidate withdrew from the race before the primary