See main article: 2008 Fifth Third Bank Tennis Championships.
Melinda Czink and Lindsay Lee-Waters were the defending champions but Czink did not compete this year, as she chose to compete at Los Angeles during the same week, reaching the third round in singles.
Lee-Waters teamed up with Melanie Oudin and lost in the final to Chan Chin-wei and Kimberly Couts. The score was 2–6, 6–3, [10–8].[1]