The 2008 ECM Prague Open was a tennis tournament played on outdoor clay courts. It was the 17th edition of the ECM Prague Open, and was part of the Tier IV Series of the 2008 WTA Tour and of the 2008 ATP Challenger Tretorn Serie+. It took place at the I. Czech Lawn Tennis Club in Prague, Czech Republic, from 28 April until 4 May 2008.
The tournament included tennis exhibition involving Thomas Muster and Ctislav Doseděl.
See main article: 2008 ECM Prague Open – Men's singles. 
Jan Hernych defeated Lukáš Dlouhý, 4–6, 6–2, 6–4
See main article: 2008 ECM Prague Open – Women's singles. 
Vera Zvonareva defeated 
Victoria Azarenka, 7–6(7–2), 6–2
See main article: 2008 ECM Prague Open – Men's doubles. Lukáš Dlouhý / Petr Pála defeated Dušan Karol / Jaroslav Pospíšil, 6–7(2–7), 6–4, [10–6]
See main article: 2008 ECM Prague Open – Women's doubles. Andrea Hlaváčková / Lucie Hradecká defeated 
Jill Craybas / Michaëlla Krajicek, 1–6, 6–3, [10–6]