| Score: | 6–1, 6–4 |
See main article: 2008 Australian Open.
Defending champion Shingo Kunieda defeated Michaël Jérémiasz in the final, 6–1, 6–4 to win the men's singles wheelchair tennis title at the 2008 Australian Open. It was his second Australian Open singles title and fourth major singles title overall.
Shingo Kunieda (champion)