| Team: | Arizona Rattlers |
| Year: | 2008 |
| Record: | 8–8 |
| Division Place: | 2nd |
| Coach: | Kevin Guy |
| Stadium: | US Airways Center |
| Playoffs: | Lost Wild Card Playoffs (Rampage) 41–48 |
| Next: | 2010 |
| Shortnavlink: | Rattlers seasons |
The Arizona Rattlers season was the 17th season for the franchise. The Rattlers finished the regular season 8–8, and made the playoffs as the 3rd seed in the American Conference. They were eliminated from the playoffs in the wild-card round, losing to the Grand Rapids Rampage, 41–48.
| Week | Date | Opponent | Result | Record | Location | Attendance | Recap | |
|---|---|---|---|---|---|---|---|---|
| 1 | March 1 | at Utah Blaze | W 63–62 | 1–0 | EnergySolutions Arena | 15,106 | Recap | |
| 2 | March 10 | Los Angeles Avengers | L 33–65 | 1–1 | US Airways Center | 11,532 | Recap | |
| 3 | March 15 | at San Jose SaberCats | L 43–63 | 1–2 | HP Pavilion | 13,625 | Recap | |
| 4 | March 21 | New York Dragons | W 62–33 | 2–2 | US Airways Center | 11,689 | Recap | |
| 5 | March 28 | at Chicago Rush | L 35–59 | 2–3 | Allstate Arena | 15,058 | Recap | |
| 6 | Bye Week | |||||||
| 7 | April 13 | at Tampa Bay Storm | W 63–62 | 3–3 | St. Pete Times Forum | 16,413 | Recap | |
| 8 | April 18 | New Orleans VooDoo | L 36–60 | 3–4 | US Airways Center | 11,749 | Recap | |
| 9 | April 26 | Georgia Force | W 66–61 | 4–4 | US Airways Center | 10,444 | Recap | |
| 10 | May 3 | at Los Angeles Avengers | L 59–66 | 4–5 | Staples Center | 13,511 | Recap | |
| 11 | May 9 | San Jose SaberCats | L 42–63 | 4–6 | US Airways Center | 11,514 | Recap | |
| 12 | May 17 | at Dallas Desperados | W 55–54 | 5–6 | American Airlines Center | 12,950 | Recap | |
| 13 | May 24 | Grand Rapids Rampage | W 52–48 | 6–6 | US Airways Center | 12,559 | Recap | |
| 14 | May 31 | at Orlando Predators | W 60–53 | 7–6 | Amway Arena | 12,821 | Recap | |
| 15 | June 8 | at Kansas City Brigade | W 73–34 | 8–6 | Sprint Center | 12,210 | Recap | |
| 16 | June 16 | Colorado Crush | L 55–62 | 8–7 | US Airways Center | 11,608 | Recap | |
| 17 | June 21 | Utah Blaze | L 45–62 | 8–8 | US Airways Center | 13,542 | Recap | |
Bye Week