See main article: 2007 Delray Beach International Tennis Championships.
Tommy Haas was the defending champion, but lost in quarterfinals to Vincent Spadea.
Xavier Malisse won in the final 5–7, 6–4, 6–4 against James Blake.
See also: 1. 
James Blake (final)
See also: 2. Tommy Haas (quarterfinals)
See also: 3. 
Xavier Malisse (champion)
See also: 4. Benjamin Becker (semifinals)
See also: 5. Florian Mayer (quarterfinals)
See also: 6. Philipp Kohlschreiber (round robin)
See also: 7. 
Guillermo García-López (quarterfinals)
See also: 8. Vincent Spadea (semifinals)
Prior to the round robin and after the completion of the qualifying draws, the 16 players with the lowest tier in the tournament (4 qualifiers, 3 wild cards and 9 based on ATP rankings) competed in the elimination round in order to get one of the 8 last spots into the round robin competition. Winners in this round entered as main entrants.
| Main draw elimination round | ||||
|---|---|---|---|---|
| Event | Winner | Loser | Score | |
| Main Entrant 1 |  Davide Sanguinetti |  Dušan Vemić [Q] | 6–2, 4–6, 6–2 | |
| Main Entrant 2 |  Alejandro Falla |  Sergiy Stakhovsky [Q] | 6–4, 6–4 | |
| Main Entrant 3 | Andrei Pavel | Ilija Bozoljac | 6–3, 1–0, retired | |
| Main Entrant 4 |  Teymuraz Gabashvili | Jan-Michael Gambill [WC] | 7–6(7–3), 6–4 | |
| Main Entrant 5 | Ryan Sweeting [WC] | Michael Russell [WC] | 7–6(7–4), 2–2, retired | |
| Main Entrant 6 | Sam Querrey | Konstantinos Economidis | 6–0, 6–2 | |
| Main Entrant 7 | Scoville Jenkins [Q] | Alex Bogdanovic | 6–3, 7–6(7–3) | |
| Main Entrant 8 | Jesse Levine [Q] |  Łukasz Kubot | 6–3, 6–2 | |
See also: 1. Santiago Giraldo (qualifying competition)
See also: 2. Hugo Armando (qualifying competition)
See also: 3. Benedikt Dorsch (first round)
See also: 4. 
Alan Mackin (first round)
See also: 5. Todd Widom (first round)
See also: 6. Michael Lammer (qualifying competition)
See also: 7. 
Frédéric Niemeyer (qualifying competition)
See also: 8. Sergiy Stakhovsky (qualified)