See main article: 2006 SAP Open.
| Champ: |  Andy Murray |
| Runner: |  Lleyton Hewitt |
| Score: | 2–6, 6–1, 7–6(7–3) |
| Draw: | 32 (4 / 3) |
| Seeds: | 8 |
| Type: | singles doubles |
| Main Name: | Pacific Coast Championships |
Andy Roddick was the defending champion, but lost in the semifinals to eventual champion Andy Murray.
Murray defeated Lleyton Hewitt 2–6, 6–1, 7–6(7–3), to become 2006 SAP Open Champion, and claim his first ever ATP Tour title.