| Gender: | Women's |
| Year: | 2006 |
| Division: | II |
| Teams: | 64 |
| Finalfourcity: | Hot Springs, Arkansas |
| Finalfourarena: | Summit Arena |
| Champions: | Grand Valley State Lakers |
| Titlecount: | 1st |
| Runnerup: | American International Yellow Jackets |
| Gamecount: | 1st |
| Semifinal1: | Chico State Wildcats |
| Finalfourcount: | 1st |
| Semifinal2: | St. Cloud State Huskies |
| Finalfourcount2: | 1st |
| Coach: | Dawn Plitzuweit |
| Coachcount: | 1st |
| Mop: | Julia Braseth |
| Mopteam: | Grand Valley State |
The 2006 NCAA Division II women's basketball tournament was the 25th annual tournament hosted by the NCAA to determine the national champion of Division II women's collegiate basketball in the United States.[1]
Grand Valley State defeated American International in the championship game, 58–52, to claim the Lakers' first NCAA Division II national title.
For the second consecutive year, the championship rounds were contested at the Summit Arena in Hot Springs, Arkansas.
Location: Eddie King Gym Host: University of Charleston
Location: Weiser Gymnasium Host: Drury University
Location: Betty Engelstad Sioux Center Host: University of North Dakota
Location: James W. Moore Fieldhouse Host: Southern Connecticut State University
Location: Wells Center Host: Henderson State University
Location: Spaulding Gym Host: Shaw University
Location: Lee Arena Host: Washburn University
Location: Sam Carver Gymnasium Host: Western Washington University
Location: Summit Arena Hosts: Henderson State University and Hot Springs Convention Center