| Year: | 2006 |
| Team: | Mississippi State Bulldogs |
| Conference: | Southeastern Conference |
| Division: | Western Division |
| Short Conf: | SEC |
| Record: | 3–9 |
| Conf Record: | 1–7 |
| Head Coach: | Sylvester Croom |
| Hc Year: | 3rd |
| Off Coach: | Woody McCorvey |
| Oc Year: | 3rd |
| Off Scheme: | West Coast |
| Def Coach: | Ellis Johnson |
| Dc Year: | 3rd |
| Stadium: | Davis Wade Stadium |
The 2006 Mississippi State Bulldogs football team represented Mississippi State University as a member of the Western Division of the Southern Conference (SEC) during the 2006 NCAA Division I FBS football season. Led by third-year head coach Sylvester Croom, the Bulldogs compiled an overall record of 3–9 with a mark of 1–7 in conference play, placing last out of six teams in the SEC's Western Division. Mississippi State played home games at Davis Wade Stadium in Starkville, Mississippi.