See main article: 2006 JPMorgan Chase Open.
The 2006 JPMorgan Chase Open singles statistics are for the 2006 WTA Tour, a Women's Tennis Association (WTA) tennis competition.
Kim Clijsters was the defending champion, but did not compete this year.
Elena Dementieva won the title, defeating Jelena Janković 6–3, 4–6, 6–4 in the final. It was her 2nd title of the year and the 6th title of her career.
The top eight seeds received a bye into the second round.