| 2006 ICC World Cricket League Africa Region Division Three | |
| Administrator: | African Cricket Association |
| Cricket Format: | 50 overs per side |
| Tournament Format: | round robin with playoffs |
| Participants: | 8 |
| Matches: | 20 |
| Most Runs: |  Kaleem Shah 313 |
| Most Wickets: |  Peter Ananya 14 |
| Next Year: | 2008 |
| Next Tournament: | 2008 ICC World Cricket League Africa Region Division Three |
The 2006 ICC World Cricket League Africa Region Division Three was a cricket tournament in South Africa, taking place between 23 April and 28 April 2006. It gave eight African Associate and Affiliate members of the International Cricket Council experience of international one-day cricket and formed part of the global World Cricket League structure.
The top team, Mozambique was promoted to Division 2.
There were 8 teams that played in the tournament. These teams were non-test member nations of the African Cricket Association. The teams that played were:
| Pool 1 | Pool 2 |
| Team qualifies for Semifinals | ||
| Team qualifies for 5th place playoff Semifinals |
----------------------------------------------------
----------------
--------------------
| Most Runs | Most Wickets | ||||||
|---|---|---|---|---|---|---|---|
| width=160 | Kaleem Shah | width=40 align=center | 313 | width=160 | Peter Ananya | width=40 align=center | 14 |
 George Kpundeh | align=center | 169 | Abubakarr Kamara | align=center | 12 | ||
| Lansana Lamin | align=center | 149 |  Zaccheus Akila | align=center | 12 | ||
| Kodom Anafie | align=center | 165 |  Srinath Vardhineni | align=center | 12 | ||
 Musaeed Qureshi | align=center | 164 | I Kara | align=center | 11 |