See main article: 2006 Copa Colsanitas Seguros Bolivar.
Emmanuelle Gagliardi and Tina Pisnik were the defending champions, but Pisnik did not compete this year. Gagliardi teamed up with Mariana Díaz Oliva and lost in first round to María José Argeri and Letícia Sobral.
Gisela Dulko and Flavia Pennetta won the title by defeating Ágnes Szávay and Jasmin Wöhr 7–6(7–1), 6–1 in the final.