| Copa América de Ciclismo | |
| Series: | 2005–2006 UCI America Tour |
| Date: | January 8, 2006 |
| Stages: | 1 |
| Distance: | 34.472 |
| Unit: | km |
| Time: | 0h 45' 25" |
| Speed: | 45.5 |
| First: | Nilceu Santos |
| First Nat: | BRA |
| Second: | Rodrigo Brito |
| Second Nat: | BRA |
| Third: | Héctor Figueiras |
| Third Nat: | BRA |
| Previous: | 2005 |
| Next: | 2007 |
The sixth edition of the Copa América de Ciclismo was held on 8 January 2006 in São Paulo, Brazil. Nilceu Santos (Scott) repeated his 2005 victory, beating Rodrigo Brito (São Caetano) and Héctor Figueiras (São Caetano) in a bunch sprint.
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