The 2006 Brasil Open was an ATP Tour men's tennis tournament held in Costa do Sauipe resort, Mata de São João, Brazil and played on outdoor clay courts. It was the sixth edition of the tournament and was held from 20 to 27 February 2006. Nicolás Massú won the singles title.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Argentina | Gastón Gaudio | 9 | 1 | |
 Spain | Juan Carlos Ferrero | 16 | 2 | |
 Italy | Filippo Volandri | 31 | 3 | |
 France | Florent Serra | 37 | 4 | |
| Argentina | Juan Ignacio Chela | 44 | 5 | |
| Nicolás Massú | 55 | 6 | ||
| Spain | Alberto Martín | 68 | 7 | |
| Boris Pašanski | 58 | 8 |
The following players received wildcards into the main draw:
The following players received entry from the qualifying draw:
The following players received entry as lucky losers:
The following player received entry due to a protected ranking:
Before the tournament
Agustín Calleri (replaced by Portas) Mariano Zabaleta (replaced by Navarro Pastor)The following pairs received wildcards into the main draw:
The following pairs received entry as alternates:
See main article: 2006 Brasil Open – Singles. Nicolás Massú defeated Alberto Martín 6–3, 6–4[2]
See main article: 2006 Brasil Open – Doubles. 
Lukáš Dlouhý / Pavel Vízner defeated 
Mariusz Fyrstenberg / Marcin Matkowski 6–1, 4–6, [10–3]
