The 2005 WNBA season was the eighth for the Washington Mystics. The Mystics gave it their all, but they fell short for the playoffs, losing a tiebreaker to the Detroit Shock.
| Round | Pick | Player | Nationality | School/Club Team | |
| 1 | 6 | Temeka Johnson (G) | LSU | ||
| 2 | 19 | Erica Taylor (G) | Louisiana Tech | ||
| 3 | 32 | Tashia Morehead (F) | Florida |
| Date | Opponent | Score | Result | Record | |
| May 21 | 60-42 | Win | 1-0 | ||
| May 22 | 67-69 | Loss | 1-1 | ||
| May 26 | 75-84 | Loss | 1-2 | ||
| June 1 | 68-77 | Loss | 1-3 | ||
| June 3 | 74-71 | Win | 2-3 | ||
| June 5 | 58-61 | Loss | 2-4 | ||
| June 7 | 62-71 | Loss | 2-5 | ||
| June 10 | 64-52 | Win | 3-5 | ||
| June 11 | 60-78 | Loss | 3-6 | ||
| June 18 | 88-78 (2OT) | Win | 4-6 | ||
| June 21 | 77-56 | Win | 5-6 | ||
| June 24 | 69-55 | Win | 6-6 | ||
| June 26 | 57-62 | Loss | 6-7 | ||
| June 28 | 66-61 (OT) | Win | 7-7 | ||
| June 30 | 65-50 | Win | 8-7 | ||
| July 7 | 62-76 | Loss | 8-8 | ||
| July 13 | 78-71 | Win | 9-8 | ||
| July 15 | 66-77 | Loss | 9-9 | ||
| July 16 | 59-73 | Loss | 9-10 | ||
| July 19 | 74-68 | Win | 10-10 | ||
| July 21 | 70-65 | Win | 11-10 | ||
| July 26 | 65-83 | Loss | 11-11 | ||
| July 28 | 73-58 | Win | 12-11 | ||
| July 29 | 58-62 | Loss | 12-12 | ||
| August 2 | 65-63 | Win | 13-12 | ||
| August 7 | 61-60 | Win | 14-12 | ||
| August 11 | 65-80 | Loss | 14-13 | ||
| August 14 | 77-80 | Loss | 14-14 | ||
| August 16 | 66-72 | Loss | 14-15 | ||
| August 18 | 57-67 | Loss | 14-16 | ||
| August 21 | 52-66 | Loss | 14-17 | ||
| August 23 | 82-69 (OT) | Win | 15-17 | ||
| August 26 | 47-81 | Loss | 15-18 | ||
| August 27 | 76-67 | Win | 16-18 |
| Player | GP | REB | AST | STL | BLK | PTS | |
| Alana Beard | 30 | 130 | 90 | 45 | 9 | 422 | |
| Chasity Melvin | 34 | 199 | 25 | 31 | 14 | 397 | |
| DeLisha Milton-Jones | 33 | 172 | 58 | 57 | 18 | 394 | |
| Temeka Johnson | 34 | 104 | 177 | 44 | 1 | 315 | |
| Charlotte Smith | 34 | 128 | 71 | 22 | 11 | 246 | |
| Coco Miller | 34 | 59 | 44 | 26 | 3 | 153 | |
| Laurie Koehn | 30 | 11 | 10 | 2 | 0 | 113 | |
| Murriel Page | 34 | 83 | 25 | 15 | 9 | 108 | |
| Nakia Sanford | 27 | 45 | 6 | 10 | 11 | 88 | |
| Kaayla Chones | 12 | 6 | 1 | 1 | 0 | 14 | |
| Tamicha Jackson | 8 | 6 | 10 | 5 | 0 | 9 | |
| Kiesha Brown | 2 | 0 | 0 | 2 | 0 | 2 | |
| Mactabene Amachree | 3 | 0 | 0 | 0 | 0 | 2 |