| Year: | 2005 |
| Team: | Tennessee State Tigers |
| Sport: | football |
| Conference: | Ohio Valley Conference |
| Short Conf: | OVC |
| Record: | 2–9 |
| Conf Record: | 1–6 |
| Head Coach: | James Webster |
| Hc Year: | 1st |
| Stadium: | The Coliseum |
The 2005 Tennessee State Tigers football team represented Tennessee State University as a member of the Ohio Valley Conference (OVC) during the 2005 NCAA Division I-AA football season. Led by first-year head coach James Webster, the Tigers compiled an overall record of 2–9, with a conference record of 1–6, and finished eighth in the OVC.