| Year: | 2005 |
| Team: | Southern Illinois Salukis |
| Sport: | football |
| Conference: | Gateway Football Conference |
| Short Conf: | Gateway |
| Tsnrank: | 7 |
| Record: | 9–4 |
| Conf Record: | 5–2 |
| Head Coach: | Jerry Kill |
| Hc Year: | 5th |
| Off Coach: | Matt Limegrover |
| Oc Year: | 5th |
| Def Coach: | Tracy Claeys |
| Dc Year: | 5th |
| Stadium: | McAndrew Stadium |
| Champion: | Gateway co-champion |
| Bowl: | NCAA Division I-AA Quarterfinal |
| Bowl Result: | L 24–38 vs. Appalachian State |
The 2005 Southern Illinois Salukis football team represented Southern Illinois University as a member of the Gateway Football Conference during the 2005 NCAA Division I-AA football season. They were led by fifth-year head coach Jerry Kill and played their home games at McAndrew Stadium in Carbondale, Illinois. The Salukis finished the season with a 9–4 record overall and a 5–2 record in conference play, making them conference co-champions. The team received an at-large bid to the Division I-AA playoffs, where they defeated Eastern Illinois before losing to Appalachian State in the quarterfinals.[1] Southern Illinois was ranked No. 7 in The Sports Network's postseason ranking of FCS teams.[2]