| Club: | São Paulo |
| Season: | 2005 |
| Manager: |  Émerson Leão(until April 17) Milton Cruz (caretaker, until April 30) Paulo Autuori |
| Mgrtitle: | Manager |
| Chairman: | Marcelo Portugal Gouvêa |
| Chrtitle: | Chairman |
| League: | Série A |
| League Result: | 11th |
| Cup1: | Campeonato Paulista |
| Cup1 Result: | Champions (21st title)[1] |
| Cup2: | Copa Libertadores |
| Cup2 Result: | Champions (3rd title)[2] |
| Cup3: | Copa Sudamericana |
| Cup3 Result: | First round |
| Cup4: | Club World Championship |
| Cup4 Result: | Champions (3st title)[3] |
| League Topscorer: | Amoroso (12) |
| Season Topscorer: | Rogério Ceni (21) |
| Highest Attendance: | 71,986 (v Atlético Paranaense in the Copa Libertadores) |
| Lowest Attendance: | 2,170 (v Brasiliense in the Campeonato Brasileiro) |
| Prevseason: | 2004 |
| Nextseason: | 2006 |
The 2005 season was São Paulo's 76th season since club's existence. In this season Tricolor won the Campeonato Paulista, league of State of São Paulo for the 21st time and the continental cup, Copa Libertadores de America, beating Atlético Paranaense in the first final with teams from the same country of tournament history, winning by 4–0 in the second match, 5–1 in aggregate. The continental title enabled São Paulo to participate of FIFA Club World Championship in the end of season when the club became a world champion for the third time (2 Intercontinental Cups), defeating the English club, European champions Liverpool in the final with a single goal scored by Mineiro in the 27th minute of first time. In the Campeonato Brasileiro São Paulo finished in 11th position and was eliminated by Internacional in first round of Copa Sudamericana.
| Games played | 79 (19 Campeonato Paulista, 14 Copa Libertadores, 42 Campeonato Brasileiro, 2 Copa Sudamericana, 2 Club World Cup) |
| Games won | 41 (14 Campeonato Paulista, 9 Copa Libertadores, 16 Campeonato Brasileiro, 0 Copa Sudamericana, 2 Club World Cup) |
| Games drawn | 18 (3 Campeonato Paulista, 4 Copa Libertadores, 10 Campeonato Brasileiro, 1 Copa Sudamericana, 0 Club World Cup) |
| Games lost | 20 (2 Campeonato Paulista, 1 Copa Libertadores, 16 Campeonato Brasileiro, 1 Copa Sudamericana, 0 Club World Cup) |
| Goals scored | 166 |
| Goals conceded | 107 |
| Goal difference | +59 |
| Best result | 6–0 (H) v Marília – Campeonato Paulista – 2005.3.19 |
| Worst result | 0–3 (A) v Internacional – Campeonato Brasileiro – 2005.10.5 0–3 (A) v Goiás – Campeonato Brasileiro – 2005.11.16 |
| Top scorer | Rogério Ceni (21 goals) |