See main article: 2005 NASDAQ-100 Open. Nadia Petrova and Meghann Shaughnessy were the defending champions, but lost in quarterfinals to Lisa Raymond and Rennae Stubbs.
Svetlana Kuznetsova and Alicia Molik won the title, defeating Raymond and Stubbs 7–5, 6–7(5–7), 6–2 in the final. It was the 12th doubles title for Kuznetsova and the 6th doubles title for Molik in their respective careers.
