See main article: 2005 Internazionali Femminili di Palermo. Anabel Medina Garrigues and Arantxa Sánchez Vicario were the defending champions, but none competed this year.
Giulia Casoni and Mariya Koryttseva won the title by defeating Klaudia Jans and Alicja Rosolska 4–6, 6–3, 7–5 in the final.