| Champ: |  Yan Zi |
| Runner: |  Nuria Llagostera Vives |
| Score: | 6–4, 4–0 retired |
| Draw: | 32 (2/4) |
| Seeds: | 8 |
| Type: | singles doubles |
See main article: article and 2005 Guangzhou International Women's Open. Li Na was the defending champion, but lost in the quarterfinals to Yan Zi.
Yan reached the final, where she was leading 6–4, 4–0 when her opponent Nuria Llagostera Vives retired due to a hamstring injury, giving Yan the title.