The Women's 4 x 400 metres relay event at the 2005 European Athletics Indoor Championships was held on March 6.
| Rank | Team | Athlete | Time | Notes | |
|---|---|---|---|---|---|
| Tatyana Levina Yuliya Pechonkina Irina Rosikhina Svetlana Pospelova | 3:28.90 | ||||
| Anna Pacholak Monika Bejnar Marta Chrust-Rożej Małgorzata Pskit | 3:29.37 | NR | |||
| Melanie Purkiss Donna Fraser Catherine Murphy Lee McConnell | 3:29.81 | NR | |||
| 4 | Antonina Yefremova Oksana Ilyushkina Liliya Pilyugina Natalya Pygyda | 3:31.67 | |||
| 5 | Cora Olivero Laia Forcadell Miriam Bravo Belén Recio | 3:39.73 | |||
| 6 | Anna Moisiadou Eleftheria Papadopoulou Maria Papadopoulou Eleni Filandra | 3:48.42 |