| Year: | 2005 |
| Team: | Charleston Southern Buccaneers |
| Sport: | football |
| Conference: | Big South Conference |
| Short Conf: | Big South |
| Record: | 7–4 |
| Conf Record: | 3–1 |
| Head Coach: | Jay Mills |
| Hc Year: | 3rd |
| Off Coach: | Jamey Chadwell |
| Oc Year: | 2nd |
| Def Coach: | Steve Barrows |
| Dc Year: | 3rd |
| Stadium: | Buccaneer Field |
| Champion: | Big South co-champion |
The 2005 Charleston Southern Buccaneers football team represented Charleston Southern University as a member of the Big South Conference during the 2005 NCAA Division I-AA football season. Led by third-year head coach Jay Mills, the Buccaneers compiled an overall record of 7–4 with a mark of 3–1 in conference play, winning a share of the Big South championship.