See main article: 2005 Acura Classic. Cara Black and Rennae Stubbs were the defending champions, but lost in the semifinals to Daniela Hantuchová and Ai Sugiyama.
Conchita Martínez and Virginia Ruano Pascual won in the final, defeating Daniela Hantuchová and Ai Sugiyama 6–7(7–9), 6–1, 7–5.
The top four seeds received a bye into the second round.