| Copa del Rey | |
| Year: | 2005–06 |
| Other Title: | 104th Copa del Rey |
| Country: |  Spain |
| Num Teams: | 82 |
| Champions: | Espanyol (4th title) |
| Runner-Up: | Zaragoza |
| Top Goal Scorer: | Ewerthon (8 goals) |
| Prevseason: | 2004–05 |
| Nextseason: | 2006–07 |
The 2005–06 Copa del Rey was the 104th staging of the Copa del Rey.
|}Bye: Real Unión and Zamora.
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| 31 August 2005 | ||||||
| Real Murcia | 1–0 | Tenerife | ||||
| Lorca Deportiva | 1–2 | Ciudad de Murcia | ||||
| Recreativo | 3–2 | Elche | ||||
| Racing Ferrol | 2–0 | Sporting Gijón | ||||
| Castellón | 0–2 | Lleida | ||||
| Hércules | 0–1 | Gimnàstic | ||||
| Albacete | 2–1 | Polideportivo Ejido | ||||
| Almería | 0–0 | Numancia | Penalties: 1–3 | |||
| Xerez | 1–1 | Valladolid | Penalties: 4–2 | |||
| Levante | 0–1 | Eibar |
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|---|---|---|---|---|---|---|
| 14/15 September 2005 | ||||||
| Baza | 2–1 | Ciudad de Murcia | ||||
| Córdoba | 0–3 | Gimnàstic | ||||
| Portugalete | 0–1 | Real Unión | ||||
| Burgos | 3–1 | Salamanca | ||||
| Águilas | 1–1 | Numancia | Penalties: 4–5 | |||
| Ceuta | 0–1 | Eibar | ||||
| Lemona | 0–2 | Lleida | ||||
| Alcoyano | 3–0 | Racing Ferrol | ||||
| Alicante | 2–0 | Recreativo | ||||
| Rayo Vallecano | 1–0 | Oviedo | ||||
| Zamora | 1–0 | Villajoyosa | ||||
| L'Hospitalet | 2–0 | Pontevedra | ||||
| Alcalá | 2–4 | Xerez | ||||
| Mérida | 2–3 | Albacete | ||||
| Tenisca | 0–0 | Real Murcia | Penalties: 3–2 | |||
| Terrassa | 2–3 | Logroñés | ||||
| Almansa | 1–2 | Las Palmas |
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|---|---|---|---|---|---|---|
| 19/20 October 2005 | ||||||
| Eibar | 1–0 | Alavés | ||||
| Xerez | 3–2 | Numancia | ||||
| Rayo Vallecano | 1–2 | Getafe | ||||
| Real Unión | 0–1 | Athletic Bilbao | ||||
| Burgos | 1–0 | Racing Santander | ||||
| Tenisca | 1–3 | Celta Vigo | ||||
| Las Palmas | 0–1 | Atlético Madrid | ||||
| Zamora | 1–1 | Real Sociedad | Penalties: 2–0 | |||
| Alicante | 1–1 | Zaragoza | Penalties: 5–6 | |||
| Alcoyano | 4–1 | Mallorca | ||||
| Logroñés | 0–1 | Lleida | ||||
| L'Hospitalet | 4–3 | Gimnàstic | ||||
| Baza | 1–1 | Málaga | Penalties: 4–3 | |||
| Albacete | 1–3 | Cádiz |
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|---|---|---|---|---|---|---|
| 9/30 November 2005 | ||||||
| Baza | 0–1 | Celta Vigo | ||||
| Lleida | 2–4 | Getafe | ||||
| L'Hospitalet | 1–3 | Athletic Bilbao | ||||
| Burgos | 0–2 | Cádiz | ||||
| Zamora | 1–1 | Eibar | Penalties: 4–3 | |||
| Xerez | 2–2 | Zaragoza | Penalties: 6–7 | |||
| Alcoyano | 0–1 | Atlético Madrid |
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See main article: article and 2006 Copa del Rey final.
| Rank | Player[1] | Club | Goals |
|---|---|---|---|
 Ewerthon | Real Zaragoza | ||
 Diego Milito | Real Zaragoza | ||
| Robinho | Real Madrid | ||
| Jesús Perera | Celta Vigo | ||
 Henrik Larsson | Barcelona | ||
 Veljko Paunović | Getafe | ||
| Luis García | Espanyol | ||