| Mgrtitle: | Manager |
| Owntitle: | Owner |
| Chrtitle: | Chairman |
| League Topscorer: | Tommaso Rocchi (16) |
| Season Topscorer: | Tommaso Rocchi (17) |
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The 2005–06 season was the 106th season in Società Sportiva Lazio's history and their 18th consecutive season in the top-flight of Italian football. Lazio finished Serie A in 6th place, but were later placed in 16th, just above the relegation zone due to involvement in the 2006 Italian football scandal.
Guglielmo Stendardo Felice Piccolo Manuel Belleri Luciano Zauri Sebastiano Siviglia
Matías Lequi Andrea Giallombardo Massimo Oddo
Cribari Cristiano Gimelli Roberto Baronio Fabio Firmani
Ousmane Dabo César Massimo Bonanni Stefano Mauri Fabio Liverani
Gaby Mudingayi
Miguel Mea Vitali Christian Manfredini
Valon Behrami Guilherme SiqueiraSee main article: 2005–06 Serie A.
Tommaso Rocchi 16 Massimo Oddo 6 (6) Paolo Di Canio 5