| Club: | RCD Espanyol |
| Season: | 2005–06 |
| Chrtitle: | President |
| Chairman: | Daniel Sánchez Llibre |
| Mgrtitle: | Head coach |
| Manager: | Miguel Ángel Lotina[1] |
| Stadium: | Estadi Olímpic Lluís Companys |
| League: | La Liga |
| League Result: | 15th |
| Cup1: | Copa del Rey |
| Cup1 Result: | Winners |
| Cup2: | UEFA Cup |
| Cup2 Result: | Round of 32 |
| Prevseason: | 2004–05 |
| Nextseason: | 2006–07 |
The 2005–06 RCD Espanyol season was RCD Espanyol's 12th consecutive season in top-division of the Spanish football league, the La Liga, and the 106th as a football club.
See main article: 2005–06 La Liga.
See main article: 2005–06 Copa del Rey.
See main article: 2005–06 UEFA Cup.
See main article: 2005–06 UEFA Cup group stage.