| Mode: | Basketball |
| Year: | 2005–06 |
| Team: | Pittsburgh Panthers |
| Conference: | Big East Conference (1979–2013) |
| Short Conf: | Big East |
| Coachrank: | 18 |
| Aprank: | 16 |
| Record: | 25–8 |
| Conf Record: | 10–6 |
| Hc Year: | 3rd |
| Ac1 Year: | 5th |
| Ac2 Year: | 3rd |
| Ac3 Year: | 5th |
| Stadium: | Petersen Events Center (Capacity: 12,508) |
| Bowl Result: | second round |
The 2005–06 Pittsburgh Panthers men's basketball team represented the University of Pittsburgh in the 2005–06 NCAA Division I men's basketball season. Led by head coach Jamie Dixon, the Panthers finished with a record of 25–8[1] and made it to the second round of the 2006 NCAA Division I men's basketball tournament.