| 2005–06 PBA season | |
| Year: | 2005–06 |
| Duration: | October 2, 2005 – July 21, 2006 |
| No Of Teams: | 9 |
| Tv: | Local: ABC International: The Filipino Channel |
| Draft: | 2005 PBA Draft |
| Top Pick: | Jay Washington |
| Picked By: | Air21 Express |
| Mvp: | James Yap |
| Conf1: | Fiesta Conference |
| Conf1 Link: | 2005–06 PBA Fiesta Conference |
| Conf1 Champ: | Red Bull Barako |
| Conf1 Runner-Up: | Purefoods Chunkee Giants |
| Conf2: | Philippine Cup |
| Conf2 Link: | 2006 PBA Philippine Cup |
| Conf2 Champ: | Purefoods Chunkee Giants |
| Conf2 Runner-Up: | Red Bull Barako |
| Prevseason Link: | 2004–05 PBA season |
| Prevseason Year: | 2004–05 |
| Nextseason Link: | 2006–07 PBA season |
| Nextseason Year: | 2006–07 |
The 2005–06 PBA season was the 31st season of the Philippine Basketball Association. It began on October 2, 2005, and ended on July 21, 2006. The season had two conferences played, the import-laiden 2005–06 San Mig Coffee Fiesta Conference and the season-ending 2006 Gran Matador Brandy Philippine Cup.
The muses for the participating teams are as follows:
| style= width="50%" | Team | style= width="50%" | Muse |
|---|---|---|---|
| Air21 Express | Bianca King | ||
| Alaska Aces | Kyla | ||
| Barangay Ginebra Kings | Gabriela Leguia | ||
| Coca-Cola Tigers | Nikki Gil | ||
| Purefoods Chunkee Giants | Kelly Misa | ||
| Red Bull Barako | Dana Gajtandzievova | ||
| San Miguel Beermen | Jenny Hernandez | ||
| Sta. Lucia Realtors | Maan Biot | ||
| Talk 'N Text Phone Pals | Kristine Hermosa |
See main article: 2005–06 PBA Fiesta Conference. Red Bull Barako won the 2005–06 Fiesta Conference defeating the Purefoods Chunkee Giants in six games. The Air21 Express defeated Barangay Ginebra Kings to capture third place in a one-game playoff.
Enrico Villanueva of Red Bull won the Best Player of the Conference honors while Purefoods' import Marquin Chandler won the Best Import Award. The league introduced a Give Me 5 Promo, in which tickets for Upper Box B and General Admission seats would cost only five pesos. The marketing scheme paid off as the league had multiple soldout games during the conference.
In the 2005 PBA All-Star Game held in Laoag City, Ilocos Norte on November 26, 2005, the North All-Stars defeated the South All-Stars. Ginebra's Jayjay Helterbrand won the All-Star Game MVP honors.
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See main article: 2006 PBA Philippine Cup. The Purefoods Chunkee Giants defeated the Red Bull Barako, 4–2, in their best-of-seven finals series to win the Philippine Cup. On the third place playoff, the Alaska Aces defeated the San Miguel Beermen.
The South All-Stars defeated the North All-Stars 122–120 in the All-Star Game held in Cagayan de Oro on April 29, 2006. Asi Taulava was named as the All-Star Game MVP.
On May 14, 2006, an incident occurred when Purefoods' Eugene Tejada suffered a career-threatening injury against Red Bull, suffering extensive neck and spinal cord injuries.
See main article: 2006 PBA Philippine Cup finals. |}