| Competition: | Martyr's Memorial A-Division League |
| Season: | 2005–2006 |
| Winners: | Manang Marsyangdi Club |
| Relegated: | Mahabir Club Boudha FC |
| Continentalcup1: | 2006 AFC President's Cup |
| Continentalcup1 Qualifiers: | Manang Marsyangdi Club |
| League Topscorer: |  Rishi Rai  Junior Obagbemiro (27) |
| Prevseason: | 2004 |
| Nextseason: | 2006–07 |
| Biggest Win: | Mahabir Club 0-8 APF Club |
| Highest Scoring: | Ranipokhari Corner Team 8-9 Machhindra FC |
The 2005–06 Martyr's Memorial A-Division League season, also known as the Martyr's Memorial San Miguel League for sponsorship reasons, was the 36th season of the A-Division League since its establishment in 1954/55. A total of 14 teams competed in the league.[1] Manang Marsyangdi Club won the league. The season began on 26 August 2005 and concluded on 21 February 2006.
APF Club made their debut in the league without being promoted before.[1]
| Team | Location | Previous Season |
|---|---|---|
| APF Club | Kathmandu | n/a |
| Nepal Police Club | 2nd | |
| New Road Team | 7th | |
| Tribhuvan Army Club | 4th | |
| Machhindra Football Club | ? (promoted from Martyr's Memorial B-Division League) | |
| Boys Union Club | 11th | |
| Manang Marshyangdi Club | 3rd | |
| Ranipokhari Corner Team | 10th | |
| Sankata Club | 8th | |
| Boudha FC | ? (promoted from Martyr's Memorial B-Division League)[2] | |
| Mahabir Club | 12th | |
| Brigade Boys Club | 9th | |
| Friends Club | Lalitpur | 5th |
| Jawalakhel YC | 6th | |
| Three Star Club | 1st |
On matchday 27, relegation-threatened Machhindra FC faced Ranipokhari Corner Team. After the match ended 9-8 for Machhindra, allegations of match fixing rose, as Machhindra needed the win while RCT's Rishi Rai, who scored all eight goals, was on course to become the league's top goalscorer. While the analysis on the allegations never concluded, All Nepal Football Association did not award the top goalscorer award this season.[1] [3]