| Club: | Lille |
| Season: | 2005–06 |
| Mgrtitle: | Head coach |
| Manager: | Claude Puel |
| Stadium: | Stadium Lille Métropole Stade de France (Champions League matches) |
| League: | Ligue 1 |
| League Result: | 3rd |
| Cup1: | Coupe de France |
| Cup1 Result: | Quarter-finals |
| Cup2: | Coupe de la Ligue |
| Cup2 Result: | Round of 16 |
| Cup3: | UEFA Champions League |
| Cup3 Result: | Group stage |
| Cup4: | UEFA Cup |
| Cup4 Result: | Round of 16 |
| League Topscorer: | Peter Odemwingie (14) |
| Season Topscorer: | Peter Odemwingie (15) |
| Average Attendance: | 13,198[1] |
| Prevseason: | 2004–05 |
| Nextseason: | 2006–07 |
The 2005–06 season was the 62nd season in the existence of Lille OSC and the club's 6th consecutive season in the top flight of French football. In addition to the domestic league, Lille participated in this season's edition of the Coupe de France, the Coupe de la Ligue, the UEFA Champions League, and the UEFA Cup. The season covered the period from 1 July 2005 to 30 June 2006.
See main article: 2005–06 Ligue 1.
See main article: 2005–06 Coupe de France.
See main article: 2005–06 Coupe de la Ligue.
See main article: 2005–06 Coupe de la Ligue.
See main article: 2005–06 UEFA Cup.
| width=15 | width=15 | width=15 | width=15 | width=145 | Name | width=100 | Ligue 1 | width=80 | width=80 | width=80 | width=80 | UEFA Cup | width=100 | Total | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 14 | FW |  | Peter Odemwingie | 14 | 0 | 0 | 0 | 1 | 15 | |||||||||||
| 2 | 23 | FW |  | Abdul Kader Keïta | 5 | 0 | 0 | 0 | 0 | 5 | |||||||||||
| 17 | MF |  | Jean Makoun | 5 | 0 | 0 | 0 | 0 | 5 | ||||||||||||
| Totals | 56 | 5 | 2 | 1 | 4 | 68 | |||||||||||||||