The 2005–06 Hellenic Football League season was the 53rd in the history of the Hellenic Football League, a football competition in England.
| Competition: | Hellenic Football League Premier Division |
| Season: | 2005–06 |
| Winners: | Didcot Town |
| Promoted: | Abingdon United Bishop's Cleeve Didcot Town |
| Relegated: | Henley Town |
| Matches: | 420 |
| Total Goals: | 1387 |
| Prevseason: | 2004–05 |
| Nextseason: | 2006–07 |
Premier Division featured 19 clubs which competed in the division last season, along with three new clubs:
Also, Carterton Town changed name to Carterton.
| Competition: | Hellenic Football League Division One East |
| Season: | 2005–06 |
| Winners: | Hounslow Borough |
| Promoted: | Hounslow Borough Bicester Town |
| Matches: | 306 |
| Total Goals: | 1198 |
| Prevseason: | 2004–05 |
| Nextseason: | 2006–07 |
Division One East featured 16 clubs which competed in the division last season, along with two clubs:
Also, Bisley Sports changed name to Bisley.
| Competition: | Hellenic Football League Division One West |
| Season: | 2005–06 |
| Winners: | Winterbourne United |
| Promoted: | Harrow Hill |
| Matches: | 306 |
| Total Goals: | 982 |
| Prevseason: | 2004–05 |
| Nextseason: | 2006–07 |
Division One West featured 14 clubs which competed in the division last season, along with five new clubs: