| Season: | 2005–06 |
| Continentalcup2 Qualifiers: | Slavia Prague Sparta Prague (via Domestic Cup) |
| League Topscorer: | Milan Ivana (11) |
| Matches: | 240 |
| Total Goals: | 567 |
| Average Attendance: | 4,085[1] |
| Nextseason: | 2006–07 |
The 2005–06 Czech First League, known as the Gambrinus liga for sponsorship reasons, was the thirteenth season of top-tier football in the Czech Republic.
| Rank | Player | Club | Goals |
|---|---|---|---|
| 1 |  Milan Ivana | Slovácko | 11 |
| 2 |  Marek Kulič | Mladá Boleslav | 10 |
| Karel Piták | Slavia Prague | ||
| Stanislav Vlček | Slavia Prague | ||
| 5 | Horst Siegl | Most | 9 |
| 6 | Luboš Pecka | Mladá Boleslav | 8 |
| Adam Varadi | Baník Ostrava | ||
| Rudolf Otepka | Marila Příbram | ||
| Libor Došek | Sparta Prague |