| Mode: | Basketball |
| Year: | 2004–05 |
| Prev Year: | 2003–04 |
| Next Year: | 2005–06 |
| Team: | Southern Illinois Salukis |
| Conference: | Missouri Valley Conference |
| Short Conf: | MVC |
| Record: | 27–8 |
| Conf Record: | 15–3 |
| Hc Year: | 1st |
| Champion: | MVC Regular season champion |
| Tourney Result: | second round |
The 2004–05 Southern Illinois Salukis men's basketball team represented Southern Illinois University Carbondale during the 2004–05 NCAA Division I men's basketball season. The Salukis were led by first-year head coach Chris Lowery and played their home games at the SIU Arena in Carbondale, Illinois as members of the Missouri Valley Conference. They finished the season 27–8, 15–3 in MVC play to finish atop the regular season standings. The Salukis were eliminated in the semifinal round of the MVC tournament, but received an at-large bid to the NCAA tournament as No. 7 seed in the Chicago region. The Salukis defeated No. 10 seed Saint Mary's[1] before falling to No. 2 seed Oklahoma State in the round of 32.[2]
|-!colspan=12 style=| Regular season|-!colspan=12 style=| Missouri Valley tournament|-!colspan=12 style=| NCAA tournament[3]
See main article: 2004–05 NCAA Division I men's basketball rankings. [4]