| Year: | 2003 |
| Team: | Louisville Cardinals |
| Conference: | Conference USA |
| Short Conf: | C-USA |
| Record: | 9–4 |
| Conf Record: | 5–3 |
| Hc Year: | 1st |
| Oc Year: | 1st |
| Def Coach: | Mike Gillhamer |
| Dc Year: | 1st |
| Bowl Result: | L 28–49 vs. Miami (OH) |
The 2003 Louisville Cardinals football team represented the University of Louisville in the 2003 NCAA Division I-A football season. The team, led by Bobby Petrino in his first year at the school, played their home games in Papa John's Cardinal Stadium.