The women's 4 x 400 metres relay event at the 2003 IAAF World Indoor Championships was held on March 16.
| Rank | Nation | Competitors | Time | Notes | |
|---|---|---|---|---|---|
| Natalya Antyukh, Yuliya Pechenkina, Olesya Zykina, Natalya Nazarova | 3:28.45 | WL | |||
| Ronetta Smith, Catherine Scott, Sheryl Morgan, Sandie Richards | 3:31.23 | ||||
| Monique Hennagan, Meghan Addy, Brenda Taylor, Mary Wineberg | 3:31.69 | ||||
| 4 | Jennifer Meadows, Danielle Halsall, Amy Spencer, Catherine Murphy | 3:32.18 | NR | ||
| 5 | Antonina Yefremova, Tetyana Debela, Nataliya Zhuravlyova-Vdovychenko, Nataliya Makukh | 3:36.18 |