The 2001 US Open was held between August 27 - September 9, 2001. It was the final Grand Slam event of 2001.
Marat Safin was unsuccessful in his title defence, being defeated in the semifinals by Pete Sampras in a rematch of the 2000 final, while Venus Williams was successful in her title defense, beating her sister Serena in the women's final. 20-year-old Australian Lleyton Hewitt won the men's title, defeating Sampras in the final. It was the second consecutive US Open final defeat for Sampras.
See main article: 2001 US Open – Men's singles. 
Lleyton Hewitt defeated 
Pete Sampras, 7–6(7–4), 6–1, 6–1
See main article: 2001 US Open – Women's singles. Venus Williams defeated Serena Williams, 6–2, 6–4
See main article: 2001 US Open – Men's doubles. Wayne Black / Kevin Ullyett defeated Donald Johnson / Jared Palmer, 7–6, 2–6, 6–3
See main article: 2001 US Open – Women's doubles. Lisa Raymond / Rennae Stubbs defeated Kimberly Po / 
Nathalie Tauziat, 6–2, 5–7, 7–5
See main article: 2001 US Open – Mixed doubles. Rennae Stubbs / Todd Woodbridge defeated Lisa Raymond / 
Leander Paes, 6–4, 5–7, [11–9]
• It was Stubbs' 2nd and last career Grand Slam mixed doubles title and her 1st and only title at the US Open.
• It was Woodbridge's 7th and last career Grand Slam mixed doubles title and his 3rd title at the US Open.
Gilles Müller defeated Yeu-Tzuoo Wang, 7–6(5), 6–2.
Marion Bartoli defeated 
Svetlana Kuznetsova, 4–6, 6–3, 6–4.
Tomáš Berdych / Stéphane Bohli defeated Brendan Evans / Brett Joelson, 6–4, 6–4.
Galina Fokina / Svetlana Kuznetsova defeated Jelena Janković / Matea Mezak, 7–5, 6–3.