| Champ: |  Lindsay Davenport |
| Runner: | Martina Hingis |
| Score: | 6–7(4–7), 6–4, 6–2 |
| Type: | singles doubles |
| Draw: | 28 (4 / 2) |
| Seeds: | 8 |
| Before Name: | Toray Pan Pacific Open – Singles |
| After Name: | Toray Pan Pacific Open – Singles |
| Main Name: | Pan Pacific Open |
Lindsay Davenport defeated the two-time defending champion Martina Hingis in the final, 6–7(4–7), 6–4, 6–2 to win the singles tennis title at the 2001 Pan Pacific Open.
A champion seed is indicated in bold text while text in italics indicates the round in which that seed was eliminated. The top four seeds received a bye to the second round.
Lindsay Davenport (champion)
Anna Kournikova (semifinals)
Sandrine Testud (second round) Elena Likhovtseva (second round) Lisa Raymond (second round)