| Competition: | Primera B de Chile |
| Season: | 2001 |
| Winners: | Deportes Temuco |
| Promoted: | Deportes Temuco Cobresal |
| Relegated: | Deportes Linares |
| League Topscorer: | Carlos Arturo Cáceres (23) |
| Prevseason: | 2000 |
| Nextseason: | 2002 |
The 2001 Primera B de Chile was the 51st completed season of the Primera B de Chile.