| Score: | 6–3, 7–6(7–3) |
| Draw: | 128 (12 / 8) |
| Seeds: | 16 |
| Before Name: | Wimbledon Championships – Women's singles |
| After Name: | Wimbledon Championships – Women's singles |
See main article: 2000 Wimbledon Championships.
Venus Williams defeated the defending champion Lindsay Davenport in the final, 6–3, 7–6(7–3) to win the ladies' singles tennis title at the 2000 Wimbledon Championships.[1] It was her first major singles title. Williams lost only one set during the entire tournament, to Martina Hingis in the quarterfinals.
See also: 1 and 1. Martina Hingis (quarterfinals)
See also: 2 and 8. 
Lindsay Davenport (final)
See also: 3 and 6. 
Mary Pierce (second round)
See also: 4 and 3. 
Conchita Martínez (second round)
See also: 5 and 2. Venus Williams (champion)
See also: 6 and 7. Monica Seles (quarterfinals)
See also: 7 and 5. Nathalie Tauziat (first round)
See also: 8 and 4. Serena Williams (semifinals)
See also: 9 and 7. Arantxa Sánchez Vicario (fourth round)
See also: 10 and 4. Sandrine Testud (first round)
See also: 11 and 1. Anke Huber (fourth round)
See also: 12 and 6. Amanda Coetzer (second round)
See also: 13 and 5. Amélie Mauresmo (first round)
See also: 14 and 2. Julie Halard-Decugis (first round)
See also: 15 and 3. 
Barbara Schett (first round)
See also: 16 and 8. 
Dominique Van Roost (first round)
See main article: 2000 Wimbledon Championships – Women's singles qualifying.