| Season: | 2000 |
| Dates: | 28 May – 26 August |
| Relegated: | - |
| League Topscorer: |  Sutee Suksomkit (Thai Farmers Bank) (16) |
| Highest Scoring: | TOT 3-6 Bangkok Metropolitan Administration (9 goals) |
| Nextseason: | 2001–02 |
The 2000 Thai Premier League consisted of 12 teams. The bottom club would be relegated to the Thailand Division 1 League. The club that came 11th would play in a relegation / promotion match against the club that came second in the Thailand Division 1 League.
Champions Royal Thai Air Force entered the next edition of the Asian Club Championship.
The league was also known as the Caltex Premier League.
The club that came 11th in the Thai Premier League was to play in a relegation / promotion match against the runner-up in the Thailand Division 1 League, but at the end of the season, Thai Farmers Bank dropped out of the league and folded.
As such, Sinthana, the club that came 11th, took their place, while TOT, the team that came 12th, would play in the relegation / promotion match.
March 27 and March 31, 2001
† TOT remain in the Thai Premier League.
Thai Farmers Bank would withdraw from the league at the end of the season due to the Asian financial crisis that initial struck in 1998. The effects would spread across Asia and many clubs now came under a huge financial burden.
Bangkok Bank won the 27th edition of the Queen's Cup and their third title overall. They defeated Sinthana 5–3 on penalties after a 2–2 draw played at Suphachalasai Stadium.
BEC Tero Sasana won their first Thailand FA Cup. It is unclear whom they beat in the final.
Sutee Suksomkit - 16 Goals[1] Thai Farmers BankThe league champion was BEC Tero Sasana. It was the team's first title.